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| Team | Matches | Wins | Draws | Losses | Goals | Points | |
| 1. | Lokomotiva Surdulica | 16 | 11 | 3 | 2 | 27-10 | 36 |
| 2. | FK Naftasi | 16 | 9 | 6 | 1 | 24-9 | 33 |
| 3. | OFK Knjaževac | 16 | 9 | 4 | 3 | 17-11 | 31 |
| 4. | Pobeda Sremski Karlovci | 16 | 7 | 4 | 5 | 25-23 | 25 |
| 5. | Retarderi | 16 | 6 | 5 | 5 | 19-18 | 23 |
| 6. | Železničar Bor | 16 | 6 | 5 | 5 | 15-16 | 23 |
| 7. | Atalanta B. C. | 16 | 5 | 5 | 6 | 15-16 | 20 |
| 8. | Novi Sad | 16 | 4 | 5 | 7 | 28-28 | 17 |
| 9. | OFK Mladenovac | 16 | 4 | 5 | 7 | 12-17 | 17 |
| 10. | Dunav Smederevska Palanka | 16 | 3 | 6 | 7 | 10-16 | 15 |
| 11. | Spartak Ivanjica | 16 | 3 | 5 | 8 | 9-19 | 14 |
| 12. | FK Slavija Beograd | 16 | 0 | 5 | 11 | 5-23 | 5 |
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Events
| Novi Sad: Junior Obrad Tešić has signed a contract | 2022-06-02 20:50:58 |
| Novi Sad: Stadium has been rebuilt | 2022-04-14 08:08:36 |
| Novi Sad: Kálmán Kézdy has been sold | 2022-04-03 21:30:57 |
| Novi Sad: Kálmán Kézdy has been placed on a transfer list | 2022-04-01 21:30:54 |
| Novi Sad: Stadium has been rebuilt | 2022-04-01 21:27:21 |
| Novi Sad: Flex Costantino has been sold | 2022-03-23 21:32:55 |
| Novi Sad: Nereo Appicciato has been bought | 2022-03-23 18:20:49 |
| Novi Sad: Bronisław Balsam has been bought | 2022-03-22 20:34:35 |
| Novi Sad: Bartolomé Antunopulos has been bought | 2022-03-22 01:37:54 |
| Novi Sad: Flex Costantino has been placed on a transfer list | 2022-03-21 21:22:03 |